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Premature Ovarian Failure

Missed or irregular periods
Night sweats
Vaginal dryness
Irritability, depression, or anxiety
Trouble sleeping
Trouble with concentration or memory
What is primary ovarian insufficiency ?
Primary ovarian insufficiency (POI), also called Premature Ovarian Failure, occurs when the ovaries stop working before a woman turns 40. 
 In Premature Ovarian Failure , the ovaries don’t produce normal amounts of Estrogen and don’t produce and release an egg each month.
What causes Premature Ovarian Failure ?
In most cases the cause of Premature Ovarian Failure is unknown. Women with
certain genetic disorders, such as Turner syndrome and Fragile X syndrome, are more likely to develop Premature Ovarian Failure. 
Also, exposure to toxins (through chemotherapy and radiation therapy) can damage genetic material in cells and lead to POI. 
Sometimes autoimmune disease—when your immune system attacks your own ovarian tissue—may be responsible for Premature Ovarian Failure .
The risk of developing Premature Ovarian Failure increases if you have a family history of the disorder.
What are the health risks of Premature Ovarian Failure ?
Because women with Premature Ovarian Failure have low levels of Estrogen at a young age, several health problems are more common than in women without Premature Ovarian Failure :
• Infertility. Most women with Premature Ovarian Failure cannot get pregnant
naturally. No known fertility treatments are effective for Premature Ovarian Failure .
Most women with Premature Ovarian Failure can carry a pregnancy but most often
need to use donor eggs.
• Osteoporosis. Low levels of Estrogen increase the risk of bone loss and fractures.
• Heart disease. Low Estrogen early in life appears to increase the risk of heart attack as a woman ages.
• Depression..
If you have Premature Ovarian Failure , you may also be more likely to develop other Hormone-related disorders. 
Women with Premature Ovarian Failure should be checked periodically for deficiencies in Thyroid and Adrenal gland hormones once every 1 to 5 years.
How is Premature Ovarian Failure diagnosed?
Your doctor will ask about your Menstrual history
and any menopause-like symptoms you may be having. 
Blood tests will be done to check hormone levels like Estrogen, FSH  and determine if your Ovaries are working properly. 
Additional tests should also be done to check for possible genetic or autoimmune conditions that may be related to the ovarian failure like Karyotyping.
How is Premature Ovarian Failure  treated?
Hormone therapy (HT) is the most common treatment. 
HT combines Estrogen and Progesterone, the sex hormones that are normally present in your body.
HT relieves menopausal symptoms and also helps prevent Osteoporosis.
HT can be taken as a pill or applied to your skin as a gel, spray, or patch. 
Vaginal rings can also supply estrogen to the body.
Usually, HT is stopped when a woman with Premature Ovarian Failure reaches the age of natural menopause (around age 50).
If you cannot or do not want to take HT, you might benefit from non-Hormonal treatments. 
In addition to medical treatment, you can lower your risk of osteoporosis and heart disease by eating a healthy diet and exercising regularly.




AED is the first Endocrine research and treatment center in Kukatpally, Hyderabad.
Run by a fully qualified endocrinologist available round the clock, AED provides both
inpatient and outpatient services at a reasonable cost..

• Drug and Dosage Standardization Done for Insulin,Diabetic Drugs, Thyroxine, HRT, HTN, Cholesterol.
• 24 hr Blood glucose monitoring with CGMS and Insulin Delivery with insulin pump.
• Specialty Care- PCOD, Obesity, Hypertension, Gynecomastia, Thyroid/Adrenal and Pitutary Tumors.
• Lab Back-Up for all Hormone assays recognised by NABL and CAP.
• All Varieties of Diabetic and Hormonal Medicines available


Ground Floor,

Challa Estate,

H.No. 301, Adjacent to Vignesh Temple,

Rd. No. 3, KPHB Colony Phase 1,

Hyderabad 500072.

Ph: 04040101539




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